Sugi Predict

Sugi Predict / Compounds / SCHEMBL829286

SCHEMBL829286

SCHEMBL829286

CCOC(=O)c1cnc(Cl)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ CA12 O43570 3/20 0.48
▸ CA1 P00915 3/20 0.48
▸ CA2 P00918 3/20 0.48
▸ CA7 P43166 3/20 0.48
▸ CA9 Q16790 3/20 0.48
▸ CA14 Q9ULX7 3/20 0.48
▸ ESR1 P03372 1/20 0.48
▸ ESR2 Q92731 1/20 0.48
▸ CYP1A2 P05177 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ MAOA P21397 1/20 0.47
▸ RAB9A P51151 4/20 0.47
▸ DGAT1 O75907 1/20 0.46
▸ NPC1 O15118 2/20 0.45
▸ MAPT P10636 2/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19343349 0.85 LMNA (0.53) CYP2C19ESR1CYP1A2LMNARAB9A
SCHEMBL2642000 0.84 CYP2C9 (0.53) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL6880667 0.82 CA12 (0.55) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL24967749 0.81 LMNA (0.55) CYP2C9CYP2C19ESR1CYP1A2LMNA
SCHEMBL19779421 0.81 CA12 (0.53) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL8091063 0.81 CYP2C9 (0.50) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL5364037 0.81 LMNA (0.56) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL12461092 0.81 CYP2C9 (0.50) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL8884857 0.81 CYP2C9 (0.50) CYP2C9CYP2C19CA12CA1CA2
SCHEMBL18198247 0.81 CYP2C9 (0.50) CYP2C9CYP2C19CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1097 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118598859-A Nitrogenous heterocyclic indole xanthine oxidase inhibitor and preparation method and application thereof 武汉工程大学 2024-09-06 — — CN claimed
CN-107922352-B Process for preparing protein deacetylase inhibitors 埃斯泰隆制药公司 2021-08-06 — — CN claimed
EP-3303304-B1 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS ACETYLON PHARMACEUTICALS INC (US) 2019-11-20 — — EP claimed
US-10144714-B2 Methods of making protein deacetylase inhibitors ACETYLON PHARMACEUTICALS, INC. (US) 2018-12-04 — — US claimed
CN-107922352-A The method for preparing protein deacetylase inhibitors 埃斯泰隆制药公司 2018-04-17 — — CN claimed
EP-3303304-A1 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS Acetylon Pharmaceuticals, Inc. (US) 2018-04-11 — — EP claimed
WO-2016200930-A9 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS ACETYLON PHARMACEUTICALS, INC. (US) 2017-02-23 — — WO claimed
WO-2016200930-A1 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS ACETYLON PHARMACEUTICALS, INC. (US) 2016-12-15 — — WO claimed
US-20160355486-A1 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS ACETYLON PHARMACEUTICALS, INC. 2016-12-08 — — US claimed
US-20260138974-A1 POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS LEUKOS BIOTECH S L (ES) 2026-05-21 — — US disclosed
US-20260138986-A1 PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES BLUEPRINT MEDICINES CORP (US) 2026-05-21 — — US disclosed
US-12624044-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-05-12 — — US disclosed
US-12624043-B2 Compositions useful for treating disorders related to kit BLUEPRINT MEDICINES CORPORATION (US) 2026-05-12 — — US disclosed
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2026-05-07 — — US disclosed
US-5298507-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-29 — — US disclosed
US-5204360-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 — — US disclosed
US-5001138-A Insecticides NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) 1991-03-19 — — US disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 — — US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 — — US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138974-A1 POTENT AND SELECTIVE COMPOUNDS AS SEROTONIN 1B RECEPTOR MODULATORS HTR3B, HTR1B, HTR1A CYP2C9 327/4885CYP2C19 184/4885CA12 3845/4885
US-12624043-B2 Compositions useful for treating disorders related to kit KIT, RET, SLC26A4 CYP2C9 2278/4885CYP2C19 1492/4885CA12 2130/4885
US-10144714-B2 Methods of making protein deacetylase inhibitors HDAC1, HDAC6, AADAC CYP2C9 4436/4885CYP2C19 4554/4885CA12 2910/4885
US-20160355486-A1 METHODS OF MAKING PROTEIN DEACETYLASE INHIBITORS HDAC1, HDAC6, AADAC CYP2C9 4436/4885CYP2C19 4554/4885CA12 2910/4885
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC3, HDAC1 CYP2C9 1886/4885CYP2C19 2720/4885CA12 1023/4885
US-12624044-B2 SMARCA degraders and uses thereof SMARCA1, SMARCC1, SMARCA2 CYP2C9 4604/4885CYP2C19 4688/4885CA12 3603/4885
US-20260138986-A1 PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES KIT, PDGFRA, PDGFRB CYP2C9 4432/4885CYP2C19 3312/4885CA12 3436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.