Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.57 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969061 | 0.80 | EGFR (0.44) | EGFRTGM2 | |
| SCHEMBL24969062 | 0.78 | MAOB (0.44) | EGFRTGM2 | |
| SCHEMBL30152292 | 0.78 | MAOB (0.44) | EGFRTGM2 | |
| SCHEMBL24969059 | 0.77 | EGFR (0.42) | EGFRTGM2 | |
| SCHEMBL30152300 | 0.75 | CYP19A1 (0.71) | CYP19A1 | |
| SCHEMBL24969070 | 0.75 | CYP19A1 (0.71) | CYP19A1 | |
| SCHEMBL14200788 | 0.74 | CYP19A1 (0.46) | CYP19A1 | |
| SCHEMBL13267881 | 0.74 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL24968851 | 0.68 | TGM2 (0.42) | BRD4EGFRTGM2 | |
| SCHEMBL30152250 | 0.68 | TGM2 (0.42) | BRD4EGFRTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |