Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.44 |
| ▸ | ITK | Q08881 | 7/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968543 | 0.88 | BRAF (0.45) | EGFRITKBRAFKDRMET | |
| SCHEMBL24968542 | 0.85 | EGFR (0.49) | EGFRITKBRAFKDRMET | |
| SCHEMBL24968537 | 0.79 | P2RX4 (0.51) | EGFRITK | |
| SCHEMBL24968822 | 0.79 | SCN9A (0.47) | EGFRITKBRAFKDRMET | |
| SCHEMBL24968534 | 0.79 | EGFR (0.46) | EGFRITKBRAFKDRMET | |
| SCHEMBL24969099 | 0.73 | EGFR (0.52) | EGFRITKBRAFKDREPHX2 | |
| SCHEMBL24969092 | 0.72 | EGFR (0.51) | EGFRITKBRAFKDREPHX2 | |
| SCHEMBL20209233 | 0.71 | EGFR (0.52) | EGFRITKBRAFKDRMET | |
| SCHEMBL22069711 | 0.70 | L3MBTL1 (0.47) | METEPHX2SCN8ASCN10AFLT3 | |
| SCHEMBL24969095 | 0.69 | EGFR (0.50) | EGFRITKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |