Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239736 | 0.85 | CYP19A1 (0.41) | CYP19A1FNTAFNTBLOXL2CYP2C9 | |
| SCHEMBL10240740 | 0.82 | HSD17B10 (0.41) | LOXL2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL10746744 | 0.80 | AOC3 (0.47) | CYP2C9CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL19750347 | 0.79 | CHRNB2 (0.56) | FNTAFNTBCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL23374745 | 0.78 | KDM4E (0.43) | CYP19A1FNTAFNTBLOXL2CYP2C9 | |
| SCHEMBL10147173 | 0.76 | ALDH1A1 (0.44) | CYP19A1CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL26724521 | 0.75 | HTT (0.43) | CYP19A1FNTAFNTBCYP2C9CYP2C19 | |
| SCHEMBL27000039 | 0.75 | MAOB (0.45) | CYP19A1FNTAFNTBCYP2C9CYP2C19 | |
| SCHEMBL12088917 | 0.74 | ADRA2B (0.42) | CYP19A1FNTAFNTBLOXL2CYP2C9 | |
| SCHEMBL27587590 | 0.72 | LOXL2 (0.43) | CYP19A1FNTAFNTBLOXL2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |