Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152325 | 1.00 | CYP3A4 (0.45) | CYP3A4CYP2D6CYP2C19CYP2C9PTGDR2 | |
| SCHEMBL3987965 | 0.82 | CFD (0.46) | CYP3A4PTGDR2ALDH1A1KDM4ETDP1 | |
| SCHEMBL5569933 | 0.80 | PTGDR2 (0.45) | CYP3A4CYP2D6CYP2C19CYP2C9PTGDR2 | |
| SCHEMBL8712221 | 0.79 | PTGDR2 (0.59) | CYP3A4CYP2D6CYP2C19CYP2C9PTGDR2 | |
| SCHEMBL30152364 | 0.79 | PTGDR2 (0.59) | CYP3A4CYP2D6CYP2C19CYP2C9PTGDR2 | |
| SCHEMBL28049660 | 0.77 | ALDH1A1 (0.43) | CYP3A4CYP2C9PTGDR2ALDH1A1KDM4E | |
| SCHEMBL3328668 | 0.76 | PTGDR2 (0.68) | CYP3A4CYP2D6CYP2C19CYP2C9PTGDR2 | |
| SCHEMBL8712410 | 0.75 | CCR5 (0.42) | CYP3A4CYP2D6CYP2C19CYP2C9PTGDR2 | |
| SCHEMBL21713935 | 0.75 | FFAR4 (0.44) | CYP3A4PTGDR2ALDH1A1KDM4EMEN1 | |
| SCHEMBL20607703 | 0.75 | XDH (0.40) | CYP3A4CYP2D6CYP2C19CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |