Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968526 | 0.81 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL24968796 | 0.77 | SCN9A (0.42) | SCN9ASCN5ALRRK2 | |
| SCHEMBL24968534 | 0.76 | EGFR (0.46) | SCN9ASCN5AMET | |
| SCHEMBL24969057 | 0.76 | SCN9A (0.44) | SCN9ASCN5ALRRK2 | |
| SCHEMBL24968847 | 0.76 | SCN9A (0.44) | SCN9ASCN5AMET | |
| SCHEMBL24969558 | 0.75 | SCN9A (0.49) | SCN9ASCN5APDE4APDE4BPDE4C | |
| SCHEMBL30152321 | 0.75 | SCN9A (0.49) | SCN9ASCN5APDE4APDE4BPDE4C | |
| SCHEMBL24968528 | 0.72 | KDM4C (0.53) | SCN9ASCN5APDE4APDE4BPDE4C | |
| SCHEMBL30152356 | 0.72 | S1PR4 (0.48) | SCN9ASCN5APDE4B | |
| SCHEMBL21190851 | 0.69 | EGFR (0.32) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |