Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495065 | 0.94 | UCHL1 (0.40) | UCHL1BCL2BCL2L1MCL1NR1H2 | |
| SCHEMBL5071356 | 0.88 | AGTR2 (0.33) | — | |
| SCHEMBL2495165 | 0.85 | UCHL1 (0.40) | UCHL1MCL1ABCB1NR1H2 | |
| SCHEMBL2501733 | 0.82 | UCHL1 (0.41) | UCHL1MCL1NR1H2 | |
| SCHEMBL5068395 | 0.81 | UCHL1 (0.30) | UCHL1 | |
| SCHEMBL5352509 | 0.80 | UCHL1 (0.42) | UCHL1MCL1NR1H2 | |
| SCHEMBL2499313 | 0.78 | UCHL1 (0.39) | UCHL1MCL1NR1H2 | |
| SCHEMBL2494481 | 0.76 | UCHL1 (0.40) | UCHL1MCL1NR1H2 | |
| SCHEMBL2502694 | 0.76 | UCHL1 (0.40) | UCHL1MCL1NR1H2 | |
| SCHEMBL5359255 | 0.76 | UCHL1 (0.54) | UCHL1MCL1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |