SCHEMBL24974388

SCHEMBL24974388

CCCOCCOCCOCCn1cc(-c2ccc(NC(=O)N3CCC(N4CCN(Cc5cc(OC)ccc5OC)C4=O)CC3)cc2)nn1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NAMPT P43490 3/20 0.41
▸ BTK Q06187 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ NLRP3 Q96P20 3/20 0.37
▸ SNCA P37840 1/20 0.37
▸ LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24974750 0.95 NAMPT (0.44) NAMPTBTKSMN1; SMN2NLRP3SNCA
SCHEMBL24974467 0.93 NAMPT (0.42) NAMPTBTKSMN1; SMN2NLRP3SNCA
SCHEMBL24974740 0.86 NAMPT (0.49) NAMPTSMN1; SMN2LMNA
SCHEMBL24974786 0.82 NAMPT (0.51) NAMPTSMN1; SMN2SNCALMNA
SCHEMBL24974640 0.78 NAMPT (0.54) NAMPTSMN1; SMN2LMNA
SCHEMBL21151296 0.77 BTK (0.49) NAMPTBTKSMN1; SMN2LMNA
SCHEMBL24974738 0.73 L3MBTL1 (0.38) NAMPT
SCHEMBL24974582 0.69 TP53 (0.52) BTK
SCHEMBL21122085 0.68 PKM (0.47) —
SCHEMBL21151290 0.66 BTK (0.50) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B NAMPT 1356/4885BTK 228/4885SMN1; SMN2 3020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback