Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629178 | 0.82 | — | — | |
| SCHEMBL1687842 | 0.82 | DRD2 (0.33) | DRD2 | |
| SCHEMBL13262133 | 0.80 | KDM4E (0.40) | KDM4ELMNAALOX15DRD2DRD4 | |
| SCHEMBL13599361 | 0.79 | QDPR (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13596992 | 0.79 | SIGMAR1 (0.44) | LMNADRD2DRD4SIGMAR1 | |
| SCHEMBL1574349 | 0.77 | DRD2 (0.35) | LMNADRD2DRD4 | |
| SCHEMBL7833304 | 0.77 | ALOX15 (0.38) | KDM4ELMNAALOX15DRD2DRD4 | |
| SCHEMBL9133084 | 0.76 | KDM4E (0.37) | KDM4ELMNAALOX15DRD2DRD4 | |
| SCHEMBL10752307 | 0.74 | QDPR (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12233782 | 0.74 | KDM4E (0.36) | KDM4ELMNAALOX15DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003862-A1 | CXCR4 MODULATORS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2023-01-26 | — | — | WO | disclosed |