SCHEMBL2497732

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2493414	0.90	CTSA (0.40)	CTSARPS6KA3CDC7PRMT5WDR77
	SCHEMBL2498708	0.87	RPS6KA3 (0.40)	CTSARPS6KA3CDC7PRMT5WDR77
	SCHEMBL2498904	0.86	CTSA (0.39)	CTSARPS6KA3HSD17B14CDC7PRMT5
	SCHEMBL2502844	0.85	HSD17B14 (0.38)	HSD17B14PRMT5WDR77MLLT3MLLT1
	SCHEMBL2493873	0.85	CTSA (0.38)	CTSARPS6KA3CDC7PRMT5WDR77
	SCHEMBL2495964	0.84	CTSA (0.39)	CTSARPS6KA3CDC7PRMT5WDR77
	SCHEMBL2496231	0.83	MAPK14 (0.37)	CTSARPS6KA3CDC7PRMT5WDR77
	SCHEMBL2499279	0.83	CTSA (0.47)	CTSARPS6KA3CDC7PRMT5WDR77
	SCHEMBL2494823	0.83	TUBB4A (0.42)	RPS6KA3PRKACAGSK3BCLK4MAP4K4
	SCHEMBL2498200	0.82	RPS6KA3 (0.40)	CTSARPS6KA3CDC7PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.