SCHEMBL24977985

SCHEMBL24977985

CC(CC(C)(C)NC(=O)C(C)(C)C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HTT P42858 1/20 0.44
RIPK1 Q13546 2/20 0.42
MAPT P10636 1/20 0.41
CYP3A4 P08684 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
TAAR1 Q96RJ0 3/20 0.40
POLB P06746 1/20 0.40
AOC3 Q16853 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12102403 0.80 CTSK (0.47) RIPK1MAPT
SCHEMBL20935939 0.80 CYP2C19 (0.60) ALDH1A1RIPK1MAPTCYP3A4CYP2C19
SCHEMBL26295783 0.77 AOC3 (0.43) SMN1; SMN2ALDH1A1KDM4EHTTRIPK1
SCHEMBL12664470 0.77 NPC1 (0.55) SMN1; SMN2ALDH1A1KDM4EHTTRIPK1
SCHEMBL28523836 0.74 ESR1 (0.43) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2C9
SCHEMBL585429 0.74 TRPA1 (0.48) RIPK1CYP3A4CYP2C19TAAR1AOC3
SCHEMBL28611553 0.73 FPR2 (0.45) SMN1; SMN2ALDH1A1CYP1A2CNR2POLB
SCHEMBL13813940 0.73 CYP3A4 (0.63) SMN1; SMN2ALDH1A1RIPK1MAPTCYP3A4
Acetic Acid SCHEMBL28405440 0.73 RIPK1 (0.47) RIPK1CYP3A4CYP2C19TAAR1AOC3
SCHEMBL25604264 0.72 KMT2A (0.44) ALDH1A1RIPK1CYP3A4CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230035986-A1 NOVEL CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2023-02-02 US disclosed