Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978949 | 0.94 | YAP1 (0.46) | P2RX7CYP3A4CYP2C9TSHRALDH1A1 | |
| SCHEMBL22433814 | 0.94 | YAP1 (0.46) | P2RX7CYP3A4CYP2C9TSHRALDH1A1 | |
| SCHEMBL24979440 | 0.86 | YAP1 (0.54) | PPARAP2RX7YAP1MAPK1 | |
| SCHEMBL24979705 | 0.85 | BACE1 (0.47) | — | |
| SCHEMBL22433654 | 0.85 | BACE1 (0.47) | — | |
| SCHEMBL22552666 | 0.84 | PPARA (0.51) | PPARACYP3A4CYP2C9TSHRALDH1A1 | |
| SCHEMBL22552668 | 0.84 | PPARA (0.51) | PPARACYP3A4CYP2C9TSHRALDH1A1 | |
| SCHEMBL12414109 | 0.82 | STS (0.44) | MEN1KMT2AABCB1 | |
| SCHEMBL20158205 | 0.81 | YAP1 (0.49) | P2RX7YAP1SYKABCB1 | |
| SCHEMBL28743990 | 0.81 | YAP1 (0.49) | P2RX7YAP1SYKABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | NPPA, LNPEP, CLPP | PPARA 455/4885P2RX7 2166/4885CYP3A4 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.