Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577164 | 0.92 | FAAH (0.49) | FAAHPSMB5EPHX2PTPN1 | |
| SCHEMBL25496961 | 0.89 | CHRNB2 (0.45) | FAAHGRIA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL26572532 | 0.89 | CHRND (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25982218 | 0.89 | REN (0.46) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL27427285 | 0.87 | CHRNB2 (0.46) | PSMB5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL25877985 | 0.87 | CHRNB2 (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23718677 | 0.87 | FAAH (0.52) | FAAHPSMB5EPHX2CHRNB2CHRNB4 | |
| SCHEMBL20345224 | 0.87 | AKT1 (0.45) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL20041046 | 0.87 | AKT1 (0.45) | FAAHPSMB5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL26154311 | 0.87 | FAAH (0.52) | FAAHPSMB5EPHX2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129345-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY DRUG CONJUGATE AND USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |