SCHEMBL24984075

SCHEMBL24984075

CCCCCCCC(CCC)c1nsc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.37
MGLL Q99685 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYSLTR2 Q9NS75 1/20 0.34
CYSLTR1 Q9Y271 1/20 0.34
NQO1 P15559 1/20 0.33
EPAS1 Q99814 2/20 0.33
CSNK1E P49674 1/20 0.32
NR1I2 O75469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24984434 0.96 FAAH (0.38) FAAHMGLLMAPTKDM4EALDH1A1
SCHEMBL24983709 0.85 MAPT (0.41) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL22436033 0.71 SMN1; SMN2 (0.51) FAAHMGLLMAPTKDM4EALDH1A1
SCHEMBL28856577 0.71 ACHE (0.42) FAAHMGLLMAPTKDM4EALDH1A1
SCHEMBL9300413 0.71 KDM4E (0.40) KDM4EALDH1A1HSD17B10
SCHEMBL24995661 0.70 KDM4E (0.39) KDM4EALDH1A1HSD17B10
SCHEMBL9228352 0.70 KDM4E (0.39) KDM4EALDH1A1HSD17B10
SCHEMBL4546569 0.69 KDM4E (0.50) MAPTKDM4EALDH1A1HSD17B10EPAS1
SCHEMBL21791910 0.69 SLC6A4 (0.42) FAAHMGLLMAPTALDH1A1CYSLTR2
SCHEMBL19308896 0.69 CNR2 (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230012655-A1 URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF UNIV TUFTS (US) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230012655-A1 URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF UMPS, UPP1, UGDH FAAH 1111/4885MGLL 2225/4885MAPT 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.