Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22918311 | 0.97 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAS1PR2NPSR1KMT2A | |
| SCHEMBL25679866 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAS1PR2NPSR1KMT2A | |
| SCHEMBL21362866 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAS1PR2NPSR1KMT2A | |
| SCHEMBL27877228 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAS1PR2NPSR1KMT2A | |
| SCHEMBL22966403 | 0.75 | LMNA (0.44) | SMN1; SMN2LMNAS1PR2NPSR1TLR7 | |
| SCHEMBL22966426 | 0.75 | LMNA (0.44) | SMN1; SMN2LMNAS1PR2NPSR1TLR7 | |
| Heptane SCHEMBL27871641 | 0.73 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAS1PR2NPSR1KMT2A | |
| SCHEMBL22966357 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAS1PR2NPSR1TLR7 | |
| Hexane SCHEMBL27871520 | 0.72 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAS1PR2NPSR1KMT2A | |
| SCHEMBL24984075 | 0.71 | FAAH (0.37) | FAAHMGLLHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200291024-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF | ABBVIE INC (US) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291024-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF | ENPP1, ENPP3, STING1 | SMN1; SMN2 3306/4885LMNA 3502/4885S1PR2 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.