Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.63 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539309 | 0.85 | MAOB (0.61) | MAOBNR4A2SRD5A2ALDH1A1NR4A1 | |
| SCHEMBL3658115 | 0.84 | MAOB (0.72) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL3658118 | 0.84 | MAOB (0.72) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL3658111 | 0.84 | MAOB (0.72) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL2152475 | 0.82 | MAOB (0.73) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL68983 | 0.79 | MAOB (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7908051 | 0.78 | SRD5A2 (0.85) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL339009 | 0.78 | NR4A2 (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL30207018 | 0.78 | NR4A2 (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL2495360 | 0.78 | MAOB (0.59) | MAOBNR4A2SMPD1SRD5A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030354-B2 | 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes | AMGEN INC. (US) | 2011-10-04 | — | — | US | disclosed |