SCHEMBL3272669

SCHEMBL3272669

C=C(C)C(=O)NCCC(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TGFBR1 P36897 1/20 0.35
ANPEP P15144 2/20 0.33
RNPEP Q9H4A4 2/20 0.33
DNPEP Q9ULA0 1/20 0.33
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1073008 0.89 ALDH1A1 (0.34) ALDH1A1TGFBR1SMN1; SMN2GAATSHR
SCHEMBL1197765 0.88 THRB (0.32) ALDH1A1TGFBR1RAB9ASMN1; SMN2GAA
SCHEMBL23269488 0.83 ALDH1A1 (0.35) ALDH1A1TGFBR1ANPEPRNPEPDNPEP
SCHEMBL553719 0.83 ALDH1A1 (0.35) ALDH1A1TGFBR1ANPEPRNPEPDNPEP
SCHEMBL20337911 0.81 KMT2A (0.35) ALDH1A1TGFBR1ANPEPRNPEPDNPEP
SCHEMBL136474 0.80 ALDH1A1 (0.39) ALDH1A1TGFBR1SMN1; SMN2GAATSHR
SCHEMBL28025797 0.79 KDM4E (0.46) ALDH1A1SMN1; SMN2TSHRL3MBTL1MTNR1A
SCHEMBL31277126 0.78 ANPEP (0.37) TGFBR1ANPEPRNPEPDNPEPRAB9A
SCHEMBL98539 0.78 TGFBR1 (0.38) ALDH1A1TGFBR1ANPEPRNPEPDNPEP
SCHEMBL3235398 0.78 ANPEP (0.52) TGFBR1ANPEPRNPEPDNPEPRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1680546-B1 TEMPORARY WET STRENGTH ADDITIVES PROCTER & GAMBLE (US) 2009-04-08 EP claimed
US-20070251657-A1 Temporary wet strength additives BARCUS ROBERT L 2007-11-01 US claimed
US-7258763-B2 Temporary wet strength additives THE PROCTER + GAMBLE COMPANY (US) 2007-08-21 US claimed
US-7217339-B2 Fibrous structures exhibiting improved wet strength properties THE PROCTER & GAMBLE COMPANY (US) 2007-05-15 US claimed
US-7125469-B2 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY (US) 2006-10-24 US claimed
EP-1680546-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2006-07-19 EP claimed
WO-2005038132-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2005-04-28 WO claimed
US-20050082024-A1 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
US-20050082023-A1 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
US-6197919-B1 ADDITION POLYMERIZATION OF ANIONIC AND CATIONIC MONOMERS; CHAIN TRANSFER HERCULES INCORPORATED 2001-03-06 US claimed
EP-0915918-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1999-05-19 EP claimed
WO-1998054237-A1 RESINS OF AMPHOTERIC ALDEHYDE POLYMERS AND USE OF SAID RESINS AS TEMPORARY WET-STRENGTH OR DRY-STRENGTH RESINS FOR PAPER HERCULES INCORPORATED (US) 1998-12-03 WO claimed
US-5138002-A Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1992-08-11 US claimed
EP-1676004-B1 FIBROUS STRUCTURES EXHIBITING IMPROVED WET STRENGTH PROPERTIES PROCTER & GAMBLE (US) 2010-11-17 EP disclosed
US-7691233-B2 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY (US) 2010-04-06 US disclosed
EP-1680546-B1 TEMPORARY WET STRENGTH ADDITIVES PROCTER & GAMBLE (US) 2009-04-08 EP disclosed
US-5008344-A Temporary wet strength resins and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1991-04-16 US disclosed
US-4981557-A Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1991-01-01 US disclosed
EP-0350276-A2 Temporary wet strength resins with nitrogen heterocyclic nonnucleophilic functionalities and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1990-01-10 EP disclosed
EP-0350277-A2 Temporary wet strength resins and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1990-01-10 EP disclosed