Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.56 |
| ▸ | PGR | P06401 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443024 | 0.87 | NR3C1 (0.62) | NR3C1PGRCYP11B2SMO | |
| SCHEMBL29496849 | 0.81 | NR3C1 (0.65) | NR3C1PGRCYP11B2SMO | |
| SCHEMBL1135795 | 0.81 | NR3C1 (0.65) | NR3C1PGRCYP11B2SMO | |
| Bromide SCHEMBL10578970 | 0.80 | NR3C1 (0.63) | NR3C1PGRCYP11B2SMO | |
| SCHEMBL25044243 | 0.77 | NOS1 (0.38) | CYP11B2 | |
| SCHEMBL2499293 | 0.76 | NR3C1 (0.51) | NR3C1PGRCYP11B2SMO | |
| SCHEMBL5135413 | 0.75 | CYP11B2 (0.71) | NR3C1PGRCYP11B2 | |
| SCHEMBL836802 | 0.73 | NPC1 (0.48) | NR3C1PGRCYP11B2SMO | |
| SCHEMBL30918005 | 0.72 | CYP11B2 (0.72) | NR3C1PGRCYP11B2SMO | |
| SCHEMBL787026 | 0.72 | RECQL (0.47) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030340-B2 | Moderators of glucocorticoids receptor; antiinflamamtory agents; chronic obstructive pulmonary disease | ASTRAZENECA AB (SE) | 2011-10-04 | — | — | US | disclosed |