SCHEMBL30918005

SCHEMBL30918005

Fc1ccc2c(cnn2-c2ccccc2)c1

nearest known ligand 0.72

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 6/20 0.72
NR3C1 P04150 12/20 0.70
CYP11B1 P15538 4/20 0.58
PGR P06401 5/20 0.58
SMO Q99835 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5135413 0.89 CYP11B2 (0.71) CYP11B2NR3C1CYP11B1PGR
SCHEMBL15839046 0.84 CYP11B2 (1.00) CYP11B2NR3C1CYP11B1PGRSMO
SCHEMBL15839177 0.82 CYP11B2 (0.70) CYP11B2NR3C1CYP11B1PGR
SCHEMBL22199134 0.81 NR3C1 (0.57) CYP11B2NR3C1CYP11B1PGRSMO
SCHEMBL15839047 0.80 CYP11B2 (1.00) CYP11B2NR3C1CYP11B1PGR
SCHEMBL839102 0.79 NR3C1 (0.54) CYP11B2NR3C1PGRSMO
SCHEMBL21295429 0.79 NR3C1 (0.54) CYP11B2NR3C1PGRSMO
SCHEMBL30127430 0.79 NR3C1 (0.54) CYP11B2NR3C1PGRSMO
SCHEMBL29496849 0.79 NR3C1 (0.65) CYP11B2NR3C1PGRSMO
SCHEMBL1135795 0.79 NR3C1 (0.65) CYP11B2NR3C1PGRSMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC BUCK INST RES AGING (US) 2024-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC DAGLA, DAGLB, MGLL CYP11B2 3663/4885NR3C1 4497/4885CYP11B1 3513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.