Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.30 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080770 | 0.95 | SOS1 (0.34) | SOS1SOS2BDKRB2 | |
| SCHEMBL19336780 | 0.85 | GNAI3 (0.34) | — | |
| SCHEMBL25701498 | 0.83 | — | — | |
| SCHEMBL26846516 | 0.81 | BDKRB2 (0.33) | BDKRB2 | |
| SCHEMBL19121218 | 0.80 | ROCK2 (0.32) | — | |
| SCHEMBL24577848 | 0.76 | ALOX15 (0.36) | — | |
| SCHEMBL9286726 | 0.76 | BDKRB2 (0.30) | BDKRB2 | |
| SCHEMBL19121494 | 0.75 | ROCK2 (0.34) | SOS1SOS2 | |
| SCHEMBL19120916 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL30203016 | 0.74 | ALOX15 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015240-A1 | TRICYCLIC FUSED PYRIMIDINE COMPOUNDS FOR USE AS HER2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-02-09 | — | — | WO | disclosed |