Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23029172 | 0.95 | OPRM1 (0.35) | OPRM1NT5EMAPTTLR2TP53 | |
| SCHEMBL23029077 | 0.90 | OPRM1 (0.34) | OPRM1NT5EF10ITGB3ITGA2B | |
| SCHEMBL30112567 | 0.87 | NT5E (0.40) | OPRM1NT5EF10ITGB3ITGA2B | |
| SCHEMBL24942508 | 0.87 | NT5E (0.40) | OPRM1NT5EF10ITGB3ITGA2B | |
| SCHEMBL18526372 | 0.85 | OPRM1 (0.37) | OPRM1NT5EMAPTTLR2KCNH2 | |
| SCHEMBL23029214 | 0.84 | — | — | |
| SCHEMBL23029076 | 0.84 | OPRM1 (0.35) | OPRM1NT5EF10MAPTTLR2 | |
| SCHEMBL18526322 | 0.84 | NT5E (0.41) | OPRM1NT5EMAPTTLR2KCNH2 | |
| SCHEMBL18526374 | 0.83 | OPRM1 (0.36) | OPRM1NT5EMAPTTLR2KCNH2 | |
| SCHEMBL29406990 | 0.83 | OPRM1 (0.36) | OPRM1NT5EMAPTTLR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230038702-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230038702-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | ATP2A2, ATP2A3, CACNB2 | OPRM1 1011/4885NT5E 1820/4885F10 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.