Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526374 | 1.00 | OPRM1 (0.36) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL23029077 | 0.95 | OPRM1 (0.34) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL23029076 | 0.93 | OPRM1 (0.35) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL19956800 | 0.92 | NT5E (0.36) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL29720293 | 0.92 | NT5E (0.35) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL18526368 | 0.92 | NT5E (0.35) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL18526372 | 0.90 | OPRM1 (0.37) | OPRM1NT5EALDH1A1MAPTLMNA | |
| SCHEMBL24942970 | 0.89 | NT5E (0.35) | OPRM1NT5EKCNH2 | |
| SCHEMBL30112665 | 0.89 | NT5E (0.35) | OPRM1NT5EKCNH2 | |
| SCHEMBL18526322 | 0.89 | NT5E (0.41) | OPRM1NT5EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260126388-A1 | 3D INTERFEROMETRIC LATTICE LIGHT-SHEET IMAGING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4704922-A2 | COMPLEMENTATION-BASED TAGS AND REPORTERS FOR DUAL-MODALITY LABELING | Promega Corporation (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-01 | — | — | US | disclosed |
| US-12440581-B2 | Fluorophores for super-resolution imaging | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-09-11 | — | — | US | disclosed |
| US-20250269046-A1 | CELLULAR UPTAKE OF LARGE BIOMOLECULES ENABLED BY CELL-SURFACE-REACTIVE CELL-PENETRATING PEPTIDE ADDITIVES | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2025-08-28 | — | — | US | disclosed |
| US-12344594-B2 | Red-shifted fluorophores | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-07-01 | — | — | US | disclosed |
| US-12332177-B2 | 3D interferometric lattice light-sheet imaging | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2025-06-17 | — | — | US | disclosed |
| US-12275767-B2 | Chemigenetic calcium indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-04-15 | — | — | US | disclosed |
| US-11708397-B2 | Chemigenetic calcium indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2023-07-25 | — | — | US | disclosed |
| WO-2023101458-A1 | COMPOSITION FOR PROMOTING CTCF-MEDIATED TRANSCRIPT CONDENSATION | 연세대학교 산학협력단 | 2023-06-08 | — | — | WO | disclosed |
| WO-2023064790-A1 | SILYL BRIDGED DYES | UNIVERSITY OF MASSACHUSETTS (US) | 2023-04-20 | — | — | WO | disclosed |
| US-20230095090-A1 | PHOTOACTIVE FLUOROPHORES AND METHODS OF IN VIVO LABELING | HOWARD HUGHES MEDICAL INSTITUTE | 2023-03-30 | — | — | US | disclosed |
| US-20230038702-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-02-09 | — | — | US | disclosed |
| WO-2022159193-A9 | PROXIMITY-DEPENDENT PHOTOACTIVATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-11-17 | — | — | WO | disclosed |
| US-11498932-B2 | Bright targetable red CA2+ indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2022-11-15 | — | — | US | disclosed |
| WO-2022180242-A2 | CELLULAR UPTAKE OF LARGE BIOMOLECULES ENABLED BY CELL-SURFACE-REACTIVE CELL-PENETRATING PEPTIDE ADDITIVES | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2022-09-01 | — | — | WO | disclosed |
| WO-2022159193-A1 | PROXIMITY-DEPENDENT PHOTOACTIVATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-07-28 | — | — | WO | disclosed |
| WO-2022046738-A1 | 3D INTERFEROMETRIC LATTICE LIGHT-SHEET IMAGING | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260126388-A1 | 3D INTERFEROMETRIC LATTICE LIGHT-SHEET IMAGING | HTR3D, LATS1, SPIN4 | OPRM1 2645/4885NT5E 3020/4885ALDH1A1 4032/4885 |
| US-20230038702-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | ATP2A2, ATP2A3, CACNB2 | OPRM1 1011/4885NT5E 1820/4885ALDH1A1 2321/4885 |
| US-12344594-B2 | Red-shifted fluorophores | TFEB, DDX21, CDC73 | OPRM1 3295/4885NT5E 3988/4885ALDH1A1 1847/4885 |
| US-11498932-B2 | Bright targetable red CA2+ indicators | ATP2A2, ATP2A3, ATP2A1 | OPRM1 1482/4885NT5E 2930/4885ALDH1A1 1952/4885 |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | TFEB, DDX21, CDC73 | OPRM1 3301/4885NT5E 3989/4885ALDH1A1 1850/4885 |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | MSN, CHN2, EFHD2 | OPRM1 49/4885NT5E 1942/4885ALDH1A1 3618/4885 |
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | AOC2, H1-2, CHAT | OPRM1 32/4885NT5E 1927/4885ALDH1A1 2761/4885 |
| US-20230095090-A1 | PHOTOACTIVE FLUOROPHORES AND METHODS OF IN VIVO LABELING | PDGFRA, FES, TIE1 | OPRM1 1916/4885NT5E 3817/4885ALDH1A1 176/4885 |
| US-20250269046-A1 | CELLULAR UPTAKE OF LARGE BIOMOLECULES ENABLED BY CELL-SURFACE-REACTIVE CELL-PENETRATING PEPTIDE ADDITIVES | GZMB, SLC7A5, SLC7A1 | OPRM1 2751/4885NT5E 248/4885ALDH1A1 3376/4885 |
| US-12440581-B2 | Fluorophores for super-resolution imaging | CHAT, FABP7, CD68 | OPRM1 869/4885NT5E 1555/4885ALDH1A1 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.