Sugi Predict

Sugi Predict / Compounds / SCHEMBL250013

SCHEMBL250013

SCHEMBL250013

N#Cc1ccc(C2=CCCCC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 2/20 0.42
▸ ACMSD Q8TDX5 2/20 0.42
▸ MMP3 P08254 1/20 0.42
▸ PTGS2 P35354 2/20 0.40
▸ KIF11 P52732 2/20 0.38
▸ CYP11B1 P15538 1/20 0.38
▸ CYP2A6 P11509 2/20 0.38
▸ LOXL2 Q9Y4K0 1/20 0.38
▸ CTSC P53634 1/20 0.37
▸ CA12 O43570 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ CA9 Q16790 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ CA3 P07451 1/20 0.37
▸ CA6 P23280 1/20 0.37
▸ CA14 Q9ULX7 1/20 0.37
▸ KCNH2 Q12809 1/20 0.36
▸ HRH3 Q9Y5N1 1/20 0.36
▸ HDAC3 O15379 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10793933 0.82 ACMSD (0.53) ACMSDPTGS2ALDH1A1KCNH2HRH3
SCHEMBL421011 0.80 CLK4 (0.45) ACMSDMAOB
SCHEMBL13455087 0.79 ACMSD (0.33) ACMSD
SCHEMBL11861884 0.77 ACMSD (0.41) CYP11B2ACMSDMMP3PTGS2CTSC
SCHEMBL22081880 0.75 HDAC1 (0.37) ACMSDHDAC3HDAC1HDAC2
SCHEMBL20401391 0.75 PSMB5 (0.44) ACMSDKCNH2HRH3
SCHEMBL23361671 0.74 EGLN2 (0.40) ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL29826032 0.74 EGLN2 (0.40) ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL3090196 0.74 HDAC1 (0.36) HDAC3HDAC1HDAC2MAOA
SCHEMBL30783242 0.74 CYP11B2 (0.46) CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330079-B1 CHOLESTERIC RESIN LAMINATE, PRODUCTION METHOD, AND USE ZEON CORP (JP) 2020-03-04 — — EP claimed
EP-2036969-B1 CHOLESTERIC LIQUID-CRYSTAL COMPOSITION, CIRCULAR POLARIZATION SEPARATION SHEET, AND USE THEREOF ZEON CORP (JP) 2012-09-05 — — EP claimed
US-20170119786-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS SAGIMET BIOSCIENCES INC. 2017-05-04 — — US disclosed
US-9624173-B2 Heterocyclic modulators of lipid synthesis 3-V BIOSCIENCES, INC. (US) 2017-04-18 — — US disclosed
US-20160102091-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2016-04-14 — — US disclosed
US-20150259292-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS SAGIMET BIOSCIENCES INC. 2015-09-17 — — US disclosed
US-20140322355-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2014-10-30 — — US disclosed
US-8871790-B2 Heterocyclic modulators of lipid synthesis 3-V BIOSCIENCES, INC. (US) 2014-10-28 — — US disclosed
EP-2401275-B1 NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY RESPIRATORIUS AB (SE) 2013-07-24 — — EP disclosed
EP-2401275-B1 NAPHTHYRIDINE DERIVATIVES HAVING BRONCHODILATING ACTIVITY RESPIRATORIUS AB (SE) 2013-07-24 — — EP disclosed
US-8415333-B2 Bronchodilating diazaheteroaryls RESPIRATORIOUS AB (SE) 2013-04-09 — — US disclosed
US-20120264737-A1 Heterocyclic Modulators of Lipid Synthesis 3-V BIOSCIENCES, INC. (US) 2012-10-18 — — US disclosed
US-20120040942-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS RESPIRATORIUS AB (SE) 2012-02-16 — — US disclosed
US-20120040942-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS RESPIRATORIUS AB (SE) 2012-02-16 — — US disclosed
EP-2401275-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS Respiratorius AB (SE) 2012-01-04 — — EP disclosed
WO-2010097410-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS RESPIRATORIUS AB (SE) 2010-09-02 — — WO disclosed
WO-2010097410-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS RESPIRATORIUS AB (SE) 2010-09-02 — — WO disclosed
EP-0548318-B1 LIQUID-CRYSTAL MATERIAL MERCK PATENT GMBH (DE) 1998-06-17 — — EP disclosed
EP-0548318-A1 LIQUID-CRYSTAL MATERIAL MERCK PATENT GmbH (DE) 1993-06-30 — — EP disclosed
WO-1993002152-A1 LIQUID-CRYSTAL MATERIAL MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1993-02-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259292-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS FASN, FADS1, FADS2 CYP11B2 225/4885ACMSD 2026/4885MMP3 4121/4885
US-20120264737-A1 Heterocyclic Modulators of Lipid Synthesis FASN, FADS1, FADS2 CYP11B2 214/4885ACMSD 1844/4885MMP3 4040/4885
US-20140322355-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS FASN, FADS1, FADS2 CYP11B2 214/4885ACMSD 1844/4885MMP3 4040/4885
US-20170119786-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS FASN, FADS1, SCD CYP11B2 275/4885ACMSD 1925/4885MMP3 3539/4885
US-20120040942-A1 NOVEL BRONCHODILATING DIAZAHETEROARYLS CHRM3, ADRB1, ADRB3 CYP11B2 72/4885ACMSD 150/4885MMP3 2938/4885
US-20160102091-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS FASN, FADS1, FADS2 CYP11B2 214/4885ACMSD 1844/4885MMP3 4040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.