Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25002690 | 0.82 | EGFR (0.57) | EGFRPLK1INSRIGF1RALK | |
| SCHEMBL25001848 | 0.76 | EGFR (0.46) | EGFRINSRIGF1RALK | |
| SCHEMBL25002391 | 0.76 | ULK1 (0.48) | EGFRINSRIGF1RALK | |
| SCHEMBL25002992 | 0.75 | EGFR (0.44) | EGFRPLK1ALK | |
| SCHEMBL25002999 | 0.74 | EGFR (0.68) | EGFR | |
| SCHEMBL25002766 | 0.74 | EGFR (0.54) | EGFR | |
| SCHEMBL23154092 | 0.74 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL25001851 | 0.73 | EGFR (0.40) | EGFRPLK1ALK | |
| SCHEMBL25001804 | 0.73 | EGFR (0.41) | EGFR | |
| SCHEMBL25002853 | 0.72 | EGFR (0.47) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129996-A1 | NOVEL AMINOPYRIMIDINE EGFR INHIBITOR | QILU PHARMACEUTICAL CO., LTD. (CN) | 2023-02-08 | — | — | EP | disclosed |