Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GPR88 | Q9GZN0 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294103 | 0.92 | FFAR1 (0.61) | FFAR1LMNAGPR88MAOAPTGS1 | |
| SCHEMBL2500159 | 0.92 | FFAR1 (0.61) | FFAR1LMNAGPR88MAOAPTGS1 | |
| Anisole SCHEMBL28132815 | 0.85 | FFAR1 (0.55) | FFAR1LMNAGPR88MAOAPTGS1 | |
| SCHEMBL13385106 | 0.82 | LMNA (0.68) | FFAR1LMNAMAOAPTGS1MTNR1A | |
| SCHEMBL17138170 | 0.79 | GPBAR1 (0.60) | FFAR1LMNAMTNR1AMTNR1BADRB2 | |
| SCHEMBL18969804 | 0.79 | LMNA (0.64) | FFAR1LMNAGPR88MAOAPTGS1 | |
| SCHEMBL96351 | 0.79 | LMNA (0.64) | FFAR1LMNAGPR88MAOAPTGS1 | |
| SCHEMBL31032827 | 0.79 | LMNA (0.64) | FFAR1LMNAGPR88MAOAPTGS1 | |
| SCHEMBL6937523 | 0.77 | FFAR1 (0.54) | FFAR1LMNAGPR88PTGS1ADRB2 | |
| SCHEMBL8912305 | 0.77 | FFAR1 (0.54) | FFAR1LMNAGPR88PTGS1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1979341-A1 | TRISUBSTITUTED AMINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088999-A1 | TRISUBSTITUTED AMINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |