Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | INMT | O95050 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001910 | 0.90 | GPR55 (0.40) | ADRB1ALOX5KDM4EALDH1A1PLA2G1B | |
| SCHEMBL2581074 | 0.80 | CYP1A2 (0.40) | SMN1; SMN2ALDH1A1INMTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10804198 | 0.79 | KEAP1 (0.43) | GAASMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL25003074 | 0.79 | MEN1 (0.47) | SMN1; SMN2KDM4EALDH1A1INMTCYP1A2 | |
| SCHEMBL25001894 | 0.79 | GAA (0.38) | GAASMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL9481121 | 0.78 | CYP1A2 (0.35) | GAASMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL25001888 | 0.76 | LMNA (0.40) | SMN1; SMN2ALOX5KDM4ERAB9AINMT | |
| SCHEMBL25002603 | 0.75 | ALDH1A1 (0.46) | ADRB1GAASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25002578 | 0.73 | TSHR (0.36) | ALDH1A1RAB9AINMTCYP1A2CYP3A4 | |
| Bromide SCHEMBL10802533 | 0.73 | ALDH1A1 (0.49) | ADRB1GAASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |