Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | INMT | O95050 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749754 | 0.73 | ALDH1A1 (0.42) | CHRNA1CHRNB2CHRNA7CHRNA4LMNA | |
| SCHEMBL30130850 | 0.73 | ALDH1A1 (0.42) | CHRNA1CHRNB2CHRNA7CHRNA4LMNA | |
| SCHEMBL7913896 | 0.65 | ALDH1A1 (0.56) | NPC1RAB9AHTTSMN1; SMN2LMNA | |
| SCHEMBL7498533 | 0.65 | CHRNB2 (0.60) | CHRNA1CHRNB2CHRNA7CHRNA4NPC1 | |
| SCHEMBL92905 | 0.63 | IDO1 (0.58) | SMN1; SMN2RECQL | |
| SCHEMBL28214655 | 0.62 | CSNK2A1 (0.33) | CHRNA1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL92958 | 0.62 | S1PR1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDRECQL | |
| SCHEMBL6113228 | 0.62 | RECQL (0.42) | NPC1RAB9AHTTSMN1; SMN2HPGD | |
| SCHEMBL23727376 | 0.62 | ALOX15 (0.44) | CHRNA1CHRNB2CHRNA7CHRNA4NPC1 | |
| SCHEMBL23749752 | 0.60 | MGLL (0.41) | HTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |