Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | HTT | P42858 | 6/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.70 |
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
| ▸ | FADS1 | O60427 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555975 | 0.91 | MAPT (0.68) | MAPTHTTPKMTP53TSHR | |
| SCHEMBL31040569 | 0.90 | TP53 (0.87) | MAPTHTTTP53TSHRMEN1 | |
| SCHEMBL4893387 | 0.90 | TP53 (0.87) | MAPTHTTTP53TSHRMEN1 | |
| SCHEMBL22103801 | 0.89 | TP53 (0.75) | MAPTHTTTP53TSHRMEN1 | |
| SCHEMBL30469272 | 0.89 | CNR1 (0.84) | MAPTHTTPKMTP53TSHR | |
| SCHEMBL4117269 | 0.89 | CNR1 (0.84) | MAPTHTTPKMTP53TSHR | |
| SCHEMBL17084260 | 0.89 | TP53 (0.84) | MAPTHTTTP53TSHRMEN1 | |
| SCHEMBL29556243 | 0.86 | TP53 (0.62) | MAPTHTTPKMTP53TSHR | |
| SCHEMBL29556076 | 0.86 | RAB9A (0.68) | MAPTHTTPKMTP53TSHR | |
| SCHEMBL29556193 | 0.86 | MAPT (0.60) | MAPTHTTPKMTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023014296-A2 | MOLECULAR GLUE AND SALL4 DEGRADER | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-02-09 | — | — | WO | disclosed |