Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meluadrine SCHEMBL120043 | 1.00 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL29508537 | 1.00 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL7317575 | 0.93 | ADRB2 (0.57) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL123344 | 0.91 | ADRB2 (0.55) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL1650082 | 0.91 | ADRB2 (0.55) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL30591457 | 0.91 | ADRB2 (0.55) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL7309792 | 0.88 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL4627723 | 0.87 | ADRB1 (0.49) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL5421707 | 0.85 | ADRB2 (0.59) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Mabuterol SCHEMBL21623862 | 0.82 | ADRB2 (0.59) | ADRB2HIF1AADRB1CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044684-B1 | Percutaneously absorbable preparation | NITTO DENKO CORP (JP) | 2004-07-28 | — | — | EP | claimed |
| US-6624181-B1 | Synergistic combination | ALTANA PHARMA AG (DE) | 2003-09-23 | — | — | US | claimed |
| EP-0842658-B1 | PHOTOSTABLE AQUEOUS SOLUTION CONTAINING BENZYL ALCOHOL DERIVATIVES | HOKURIKU PHARMACEUTICAL (JP) | 2003-05-21 | — | — | EP | claimed |
| US-6162833-A | Photostable aqueous solution comprising benzyl alcohol derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2000-12-19 | — | — | US | claimed |
| EP-1044684-A2 | Percutaneously absorbable preparation | NITTO DENKO CORPORATION (JP) | 2000-10-18 | — | — | EP | claimed |
| US-5952387-A | AN AQUEOUS SOLUTION COMPRISING AN OPTICAL ACTIVE ALPHA-((TERT-BUTYLAMINO)METHYL)-2-CHLORO-4-HYDROXYBENZYL ALCOHOL; USE AS A UTERINE RELAXING AGENT, BLADDER RELAXING AGENT; THERAPEUTIC TREATMENT OF PREMATURE LABOR | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-14 | — | — | US | claimed |
| US-4018818-A | Hydroxyl-substituted 2-chloro-α-(tert-butylaminomethyl)-benzylalcohols | HOKURIKU PHARMACEUTICAL CO., LTD. (JA) | 1977-04-19 | — | — | US | claimed |
| JP-9104662-A | — | — | None | — | — | JP | disclosed |
| JP-10152434-A | — | — | None | — | — | JP | disclosed |
| JP-4178356-A | — | — | None | — | — | JP | disclosed |
| JP-4308556-A | — | — | None | — | — | JP | disclosed |
| CN-112279808-B | Cystic fibrosis transmembrane conductance regulator modulators | 弗特克斯药品有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-112250627-B | Cystic fibrosis transmembrane conductance regulator modulators | 弗特克斯药品有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-1998013035-A1 | PERCUTANEOUS PREPARATIONS | NITTO DENKO CORPORATION (JP) | 1998-04-02 | — | — | WO | disclosed |
| JP-H09104662-A | BENZYLALCOHOL DERIVATIVE-CONTAINING AQUEOUS SOLUTION STABLE AGAINST LIGHT | HOKURIKU SEIYAKU CO LTD | 1997-04-22 | — | — | JP | disclosed |
| WO-1997005860-A1 | PHOTOSTABLE AQUEOUS SOLUTION CONTAINING BENZYL ALCOHOL DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-02-20 | — | — | WO | disclosed |
| EP-0420120-B1 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL (JP) | 1994-08-31 | — | — | EP | disclosed |
| JP-H04308556-A | METHOD FOR RACEMIZING OPTICALLY ACTIVE BENZYL ALCOHOL DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1992-10-30 | — | — | JP | disclosed |
| JP-H04178356-A | OPTICALLY ACTIVE BENZYLALCOHOL DERIVATIVE AND ITS USE | HOKURIKU SEIYAKU CO LTD | 1992-06-25 | — | — | JP | disclosed |
| EP-0420120-A2 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |