Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meluadrine SCHEMBL250026 | 1.00 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL29508537 | 1.00 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL7317575 | 0.93 | ADRB2 (0.57) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL123344 | 0.91 | ADRB2 (0.55) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL1650082 | 0.91 | ADRB2 (0.55) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL30591457 | 0.91 | ADRB2 (0.55) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL7309792 | 0.88 | ADRB2 (0.65) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| SCHEMBL4627723 | 0.87 | ADRB1 (0.49) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Meluadrine SCHEMBL5421707 | 0.85 | ADRB2 (0.59) | ADRB2HIF1AADRB1CYP2D6NFKB1 | |
| Mabuterol SCHEMBL21623862 | 0.82 | ADRB2 (0.59) | ADRB2HIF1AADRB1CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126138-B1 | AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS | INVOX BELGIUM NV (BE) | 2024-10-16 | — | — | EP | claimed |
| EP-4126138-A1 | AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS | Softhale NV (BE) | 2023-02-08 | — | — | EP | claimed |
| CN-115485000-A | Aerosol delivery of at least two liquid compositions | 索芙特海尔公司 | 2022-12-16 | — | — | CN | claimed |
| WO-2019178267-A2 | INDUCTIVE REGENERATION OF THE AIRWAY BY TRANSCRIPTIONAL FACTOR MODULATION OF GLANDULAR MYOEPITHELIAL STEM CELLS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2019-09-19 | — | — | WO | claimed |
| US-10377779-B2 | Carbonate prodrugs and methods of using the same | ACORDA THERAPEUTICS, INC. (US) | 2019-08-13 | — | — | US | claimed |
| US-20190125699-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | CIPHER PHARMACEUTICALS INC. (CA) | 2019-05-02 | — | — | US | claimed |
| US-20180200234-A1 | COMBINATIONS COMPRISING ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS | ALMIRALL, S.A. (ES) | 2018-07-19 | — | — | US | claimed |
| US-20180086778-A1 | CARBONATE PRODRUGS AND METHODS OF USING THE SAME | NEUROGESX, INC. | 2018-03-29 | — | — | US | claimed |
| EP-2961730-A2 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XenoPort, Inc. (US) | 2016-01-06 | — | — | EP | claimed |
| US-20150158809-A9 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XENOPORT, INC. (US) | 2015-06-11 | — | — | US | claimed |
| WO-2005014044-A1 | MEDICAMENTS FOR INHALATION COMPRISING BETAMIMETICS AND AN ANTICHOLINERGIC | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-17 | — | — | WO | claimed |
| WO-2005013992-A1 | MEDICAMENTS FOR INHALATION COMPRISING BETAMIMETICS AND AN ANTICHOLINERGIC AGENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-17 | — | — | WO | claimed |
| US-20050026948-A1 | Medicaments for inhalation comprising an anticholinergic and a betamimetic | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-02-03 | — | — | US | claimed |
| US-6624181-B1 | Synergistic combination | ALTANA PHARMA AG (DE) | 2003-09-23 | — | — | US | claimed |
| US-6569903-B2 | Comprises beta-adrenergic receptor agonist such as clenbuterol; improves tear secretion; reduced side effects on the heart | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-27 | — | — | US | claimed |
| EP-0842658-B1 | PHOTOSTABLE AQUEOUS SOLUTION CONTAINING BENZYL ALCOHOL DERIVATIVES | HOKURIKU PHARMACEUTICAL (JP) | 2003-05-21 | — | — | EP | claimed |
| US-20030008805-A1 | Ophthalmic compositions | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2003-01-09 | — | — | US | claimed |
| EP-1153614-A1 | OPHTHALMIC COMPOSITIONS | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2001-11-14 | — | — | EP | claimed |
| US-6162833-A | Photostable aqueous solution comprising benzyl alcohol derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2000-12-19 | — | — | US | claimed |
| US-5952387-A | AN AQUEOUS SOLUTION COMPRISING AN OPTICAL ACTIVE ALPHA-((TERT-BUTYLAMINO)METHYL)-2-CHLORO-4-HYDROXYBENZYL ALCOHOL; USE AS A UTERINE RELAXING AGENT, BLADDER RELAXING AGENT; THERAPEUTIC TREATMENT OF PREMATURE LABOR | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-09-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026948-A1 | Medicaments for inhalation comprising an anticholinergic and a betamimetic | CHRM1, CHRND, CHRM3 | ADRB2 5/4885HIF1A 2247/4885ADRB1 4/4885 |
| US-20180200234-A1 | COMBINATIONS COMPRISING ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS | ADRB2, ADRB3, CHRM3 | ADRB2 1/4885HIF1A 3593/4885ADRB1 5/4885 |
| US-20150158809-A9 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | CPS1, CA7, NAAA | ADRB2 3813/4885HIF1A 2396/4885ADRB1 3375/4885 |
| US-10377779-B2 | Carbonate prodrugs and methods of using the same | CA6, CA7, CA4 | ADRB2 4334/4885HIF1A 413/4885ADRB1 4090/4885 |
| US-20180086778-A1 | CARBONATE PRODRUGS AND METHODS OF USING THE SAME | CA6, CA7, CA4 | ADRB2 4334/4885HIF1A 413/4885ADRB1 4090/4885 |
| US-20190125699-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885HIF1A 2127/4885ADRB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.