Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590233 | 0.78 | INMT (0.57) | INMTKDM4ENPC1LMNAMAPT | |
| SCHEMBL2036528 | 0.64 | TSHR (0.59) | LMNANFKB1ALDH1A1 | |
| SCHEMBL11983441 | 0.63 | INMT (0.41) | INMTKDM4ENPC1LMNAMAPT | |
| SCHEMBL3716092 | 0.62 | PER2 (0.36) | ALDH1A1 | |
| SCHEMBL13847711 | 0.61 | ALDH1A1 (0.41) | ALDH1A1DRD2 | |
| SCHEMBL8290941 | 0.61 | ALDH1A1 (0.56) | SMN1; SMN2TDP1ALDH1A1DRD2 | |
| SCHEMBL4958458 | 0.61 | ALDH1A1 (0.56) | KDM4ENPC1LMNARAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4109695 | 0.60 | ALDH1A1 (0.43) | ALDH1A1DRD2 | |
| SCHEMBL3547090 | 0.60 | CACNA1H (0.36) | ALDH1A1 | |
| SCHEMBL10661826 | 0.60 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015156-A1 | PYRROLOPYRIDINE-3- AND 4-CARBOXAMIDE COMPOSITIONS AND METHODS FOR CELLULAR PROLIFERATION | HUDSPETH A JAMES (US) | 2023-02-09 | — | — | WO | disclosed |