Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25003821 | 0.85 | HDAC1 (0.64) | SCN10AHDAC1KDM1AHDAC2HDAC8 | |
| SCHEMBL25002913 | 0.84 | KDM4E (0.57) | SCN10AHDAC1KDM1AHDAC2HDAC8 | |
| SCHEMBL25003135 | 0.84 | ALDH1A1 (0.61) | SCN10AHDAC1KDM1AHDAC2HDAC8 | |
| SCHEMBL25003799 | 0.82 | HDAC1 (0.49) | SCN10AHDAC1KDM1AHDAC2HDAC8 | |
| SCHEMBL25003823 | 0.82 | CYP2D6 (0.51) | SCN10AHDAC1KDM1AHDAC2HDAC8 | |
| SCHEMBL25003141 | 0.80 | KMO (0.48) | ALDH1A1TP53LMNAMAPK1MAPT | |
| SCHEMBL25003825 | 0.80 | SCN10A (0.68) | SCN10AHDAC1KDM1AHDAC2HDAC8 | |
| SCHEMBL25003138 | 0.79 | FDPS (0.57) | ALDH1A1TP53LMNAMAPK1MAPT | |
| SCHEMBL25003812 | 0.78 | MAP4K4 (0.57) | HDAC1KDM1AHDAC2HDAC8HDAC6 | |
| SCHEMBL3000272 | 0.78 | KAT6A (0.60) | HDAC1KDM1AALDH1A1KMT2ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010192-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2023-02-09 | — | — | WO | disclosed |