Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25004335 | 0.84 | TRPM5 (0.42) | PSMD14COPS5TRPM5SSTR1SSTR4 | |
| SCHEMBL25005707 | 0.80 | SLC6A4 (0.44) | KDM4EKDM1APSMD14COPS5SLC6A4 | |
| SCHEMBL25005282 | 0.75 | SLC6A4 (0.57) | KDM1ASLC6A4CNR2MAOBALDH1A1 | |
| SCHEMBL30224671 | 0.75 | KDM4E (0.34) | KDM4EKDM1ASLC6A4CNR1CNR2 | |
| SCHEMBL23717257 | 0.72 | PSMD14 (0.42) | KDM4EPSMD14COPS5CNR1CNR2 | |
| SCHEMBL3051052 | 0.71 | PSMD14 (0.41) | KDM4EPSMD14COPS5CNR1CNR2 | |
| SCHEMBL25004312 | 0.71 | KDM1A (0.31) | KDM1AMAOB | |
| SCHEMBL30224542 | 0.71 | SYK (0.34) | KDM4EKDM1ACNR1CNR2 | |
| SCHEMBL25005545 | 0.71 | HRH3 (0.43) | KDM1AMAOBSSTR4KCNH2 | |
| SCHEMBL25004338 | 0.70 | KDM1A (0.30) | KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039553-A1 | CD73 COMPOUNDS | ENTPD5, ENTPD1, NT5E | KDM4E 944/4885KDM1A 2052/4885PSMD14 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.