Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224563 | 0.87 | TRPM5 (0.39) | TRPM5 | |
| SCHEMBL30224533 | 0.80 | SLC6A4 (0.50) | KDM1ASLC6A4MAOB | |
| SCHEMBL30224216 | 0.76 | — | — | |
| SCHEMBL30224580 | 0.76 | HRH3 (0.38) | KDM1AMAOB | |
| SCHEMBL25005258 | 0.75 | KDM4E (0.38) | KDM4EKDM1ACNR1CNR2SLC6A4 | |
| SCHEMBL25005707 | 0.75 | SLC6A4 (0.44) | KDM4EKDM1ACNR1CNR2SLC6A4 | |
| SCHEMBL30181776 | 0.74 | HTR2C (0.50) | KDM1A | |
| SCHEMBL30181836 | 0.73 | CHRNB2 (0.44) | KDM1A | |
| SCHEMBL30224864 | 0.73 | CHRNB2 (0.44) | KDM1A | |
| SCHEMBL30181642 | 0.73 | KDM1A (0.54) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |