Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444972 | 0.81 | PTGS2 (0.35) | CHRNB2CHRNA4NPC1RAB9ASLC6A3 | |
| SCHEMBL3902761 | 0.80 | PTGS2 (0.43) | CHRNB2CHRNA4NPC1RAB9ASLC6A3 | |
| SCHEMBL3902729 | 0.79 | HRH3 (0.37) | — | |
| SCHEMBL5620740 | 0.72 | — | — | |
| SCHEMBL2779049 | 0.71 | PTGS2 (0.38) | CHRNB2CHRNA4NPC1RAB9ASLC6A3 | |
| SCHEMBL10735200 | 0.66 | TAAR1 (0.44) | SLC6A3TSHRSLC18A3 | |
| SCHEMBL10742513 | 0.66 | KDM4E (0.39) | RAB9ASLC6A3CD274 | |
| SCHEMBL3900259 | 0.64 | APP (0.41) | CHRNB2CHRNA4NPC1RAB9ALMNA | |
| SCHEMBL3900801 | 0.63 | KDM4E (0.44) | CHRNB2CHRNA4NPC1RAB9ASLC6A3 | |
| SCHEMBL21461389 | 0.62 | LMNA (0.43) | LMNATSHRHRH1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765894-B2 | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS, LLC (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110244368-A1 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-10-06 | — | — | US | disclosed |