SCHEMBL2500739

SCHEMBL2500739

Oc1cc(N2CCCC2)ccc1Cc1ccc(N2CCCC2)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 3/20 0.43
▸ ALDH1A1 P00352 6/20 0.42
▸ MAPT P10636 5/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ KMT2A Q03164 4/20 0.42
▸ ALOX15 P16050 4/20 0.42
▸ L3MBTL1 Q9Y468 4/20 0.42
▸ GAA P10253 3/20 0.42
▸ S100B P04271 2/20 0.42
▸ MAPK1 P28482 2/20 0.42
▸ HTT P42858 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ PKM P14618 1/20 0.42
▸ IP6K1 Q92551 1/20 0.41
▸ PRMT6 Q96LA8 1/20 0.40
▸ HSD17B10 Q99714 4/20 0.40
▸ KDM4E B2RXH2 4/20 0.40
▸ HPGD P15428 3/20 0.40
▸ NPC1 O15118 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2477313 0.98 ALDH1A1 (0.44) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL1599647 0.85 MAPT (0.45) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL2475418 0.84 PRKDC (0.58) ALDH1A1MAPTMEN1KMT2AALOX15
SCHEMBL1599671 0.84 BCHE (0.42) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL1599621 0.84 HTT (0.46) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL1599706 0.82 BCHE (0.43) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL7296560 0.79 TERT (0.48) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL2939766 0.78 DRD2 (0.46) TERTALDH1A1MAPTMEN1KMT2A
SCHEMBL10804218 0.78 ALDH1A1 (0.50) TERTALDH1A1MAPTMEN1KMT2A
Bromide SCHEMBL7294983 0.78 TERT (0.47) TERTALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4327874-A2 3,6-DISUBSTITUTED XANTHYLIUM SALTS WisTa Laboratories Ltd. (SG) 2024-02-28 — — EP disclosed
EP-4327874-A2 3,6-DISUBSTITUTED XANTHYLIUM SALTS WisTa Laboratories Ltd. (SG) 2024-02-28 — — EP disclosed
EP-3689346-B1 3,6-DISUBSTITUTED XANTHYLIUM SALTS FOR TREATING TAUOPATHIES WISTA LAB LTD (SG) 2024-01-24 — — EP disclosed
EP-3689346-B1 3,6-DISUBSTITUTED XANTHYLIUM SALTS FOR TREATING TAUOPATHIES WISTA LAB LTD (SG) 2024-01-24 — — EP disclosed
EP-3689346-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WisTa Laboratories Ltd. (SG) 2020-08-05 — — EP disclosed
EP-3112358-B1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LAB LTD (SG) 2020-04-29 — — EP disclosed
US-10399955-B2 3,6-disubstituted xanthylium salts WISTA LABORATORIES LTD. (SG) 2019-09-03 — — US disclosed
US-10399955-B2 3,6-disubstituted xanthylium salts WISTA LABORATORIES LTD. (SG) 2019-09-03 — — US disclosed
US-20170088534-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LABORATORIES LTD. (SG) 2017-03-30 — — US disclosed
US-20170088534-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LABORATORIES LTD. (SG) 2017-03-30 — — US disclosed
US-20140161731-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LABORATORIES LTD. (SG) 2014-06-12 — — US disclosed
US-8658665-B2 3,6-disubstituted xanthylium salts and use thereof in treatment of tauopathies WISTA LABORATORIES LTD. (SG) 2014-02-25 — — US disclosed
US-8658665-B2 3,6-disubstituted xanthylium salts and use thereof in treatment of tauopathies WISTA LABORATORIES LTD. (SG) 2014-02-25 — — US disclosed
US-8658665-B2 3,6-disubstituted xanthylium salts and use thereof in treatment of tauopathies WISTA LABORATORIES LTD. (SG) 2014-02-25 — — US disclosed
US-20110300074-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LABORATORIES LTD. (SG) 2011-12-08 — — US disclosed
US-20110300074-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LABORATORIES LTD. (SG) 2011-12-08 — — US disclosed
US-20110300074-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS WISTA LABORATORIES LTD. (SG) 2011-12-08 — — US disclosed
EP-2373660-A2 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS Wista Laboratories Ltd. (SG) 2011-10-12 — — EP disclosed
WO-2010067078-A2 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS WISTA LABORATORIES LTD. (SG) 2010-06-17 — — WO disclosed
WO-2010067078-A2 3,6-DISUBSTITUTED XANTHYLIUM SALTS AS MEDICAMENTS WISTA LABORATORIES LTD. (SG) 2010-06-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140161731-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS MAPT, PSEN2, PSEN1 TERT 1191/4885ALDH1A1 4669/4885MAPT 1/4885
US-10399955-B2 3,6-disubstituted xanthylium salts MAPT, PSEN2, PSEN1 TERT 1191/4885ALDH1A1 4669/4885MAPT 1/4885
US-20170088534-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS MAPT, PSEN2, PSEN1 TERT 1191/4885ALDH1A1 4669/4885MAPT 1/4885
US-20110300074-A1 3,6-DISUBSTITUTED XANTHYLIUM SALTS MAPT, PSEN2, PSEN1 TERT 615/4885ALDH1A1 3541/4885MAPT 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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