Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | S100B | P04271 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7294983 | 0.98 | TERT (0.47) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10804218 | 0.98 | ALDH1A1 (0.50) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19381143 | 0.83 | ALDH1A1 (0.58) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13182828 | 0.81 | ADRB1 (0.56) | ALDH1A1HTTLMNAKDM4ETP53 | |
| SCHEMBL11791151 | 0.81 | PRKDC (0.65) | ALDH1A1MEN1KMT2AMAPTALOX15 | |
| SCHEMBL19381146 | 0.81 | ALDH1A1 (0.61) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19381288 | 0.81 | ALDH1A1 (0.61) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1599743 | 0.81 | ALDH1A1 (0.49) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19381286 | 0.81 | ALDH1A1 (0.61) | TERTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2939766 | 0.81 | DRD2 (0.46) | TERTALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381235-A2 | Pyrrolidine compound and pharmaceutical use | Eisai Co., Ltd. (JP) | 1990-08-08 | — | — | EP | claimed |
| EP-0641320-B1 | SUBSTITUTED (S)-3-PHENYLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR ANTAGONISTS | UPJOHN CO (US) | 2001-05-30 | — | — | EP | disclosed |
| EP-0381235-A2 | Pyrrolidine compound and pharmaceutical use | Eisai Co., Ltd. (JP) | 1990-08-08 | — | — | EP | disclosed |