Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25007227 | 0.78 | PTGIR (0.36) | PTGIRPPARA | |
| SCHEMBL30500519 | 0.69 | PSMB5 (0.49) | AGXTDRD2OPRM1DRD3OPRD1 | |
| SCHEMBL11515483 | 0.69 | PSMB5 (0.49) | AGXTDRD2OPRM1DRD3OPRD1 | |
| SCHEMBL14402816 | 0.69 | MME (0.45) | MMP2MMP3PTGS2MMEACE | |
| SCHEMBL25008019 | 0.68 | PNMT (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10599359 | 0.67 | PSMB5 (0.48) | MMP2MMP3AGXTDRD2OPRM1 | |
| SCHEMBL6059834 | 0.67 | LPL (0.54) | GPR84PPARAAGXTDRD2OPRM1 | |
| SCHEMBL3126881 | 0.66 | LPL (0.56) | PPARADRD2OPRM1DRD3OPRD1 | |
| SCHEMBL27694667 | 0.66 | LPL (0.56) | PPARADRD2OPRM1DRD3OPRD1 | |
| SCHEMBL5551488 | 0.66 | LPL (0.53) | GPR84PPARAAGXTDRD2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |