Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25008063 | 0.78 | MMP2 (0.39) | PTGIRPPARA | |
| SCHEMBL25006442 | 0.68 | PTGIR (0.37) | PTGIRPPARALPLLIPG | |
| SCHEMBL25008020 | 0.67 | LTB4R (0.30) | LTB4R | |
| SCHEMBL25008019 | 0.67 | PNMT (0.37) | — | |
| SCHEMBL16951379 | 0.63 | LPL (0.50) | PPARAPPARGLPLLIPGCYP4F2 | |
| SCHEMBL25008044 | 0.63 | CA1 (0.34) | — | |
| SCHEMBL27875968 | 0.62 | LPL (0.46) | PPARAPPARGLPLLIPGCYP4F2 | |
| SCHEMBL23943122 | 0.61 | MEN1 (0.34) | — | |
| SCHEMBL9789538 | 0.61 | PPARA (0.65) | PPARAPPARG | |
| SCHEMBL14176569 | 0.61 | PPARA (0.65) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |