SCHEMBL25008485

SCHEMBL25008485

NCc1ccc(-c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.67
MAPK13 O15264 9/20 0.65
MAPK12 P53778 9/20 0.65
MAPK11 Q15759 9/20 0.65
MAPK14 Q16539 9/20 0.65
GCGR P47871 5/20 0.65
BRAF P15056 3/20 0.64
RAF1 P04049 4/20 0.63
MAPK9 P45984 1/20 0.62
NOX1 Q9Y5S8 1/20 0.60
PTPN1 P18031 1/20 0.58
TP53 P04637 1/20 0.57
MAPT P10636 1/20 0.57
KDM4E B2RXH2 1/20 0.56
ALDH1A1 P00352 1/20 0.56
GLA P06280 1/20 0.56
GAA P10253 1/20 0.56
HPGD P15428 1/20 0.56
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7236344 0.93 ALOX5 (0.79) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL16511391 0.93 ALOX5 (0.79) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL5074753 0.87 MAPK13 (0.83) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL28017623 0.86 MAPK13 (0.66) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL16667652 0.85 MAPK13 (0.83) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL104130 0.85 MAPK13 (0.82) ALOX5MAPK13MAPK12MAPK11MAPK14
Benzene SCHEMBL28852698 0.85 MAPK13 (0.82) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL4408322 0.84 BRAF (0.86) ALOX5MAPK13MAPK12MAPK11MAPK14
SCHEMBL28776152 0.83 TAAR1 (0.50) ALOX5MAPK13MAPK12MAPK11MAPK14
Methane SCHEMBL3278320 0.83 MAPK13 (0.79) ALOX5MAPK13MAPK12MAPK11MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4378930-B1 FLUOROPOLYETHER COMPOUND UNIV TOKYO (JP) 2025-12-10 EP disclosed
US-20240182641-A1 FLUOROPOLYETHER COMPOUND THE UNIVERSITY OF TOKYO (JP) 2024-06-06 US disclosed
EP-4378930-A1 FLUOROPOLYETHER COMPOUND The University of Tokyo (JP) 2024-06-05 EP disclosed
CN-117794981-A Fluoropolyether compound 国立大学法人东京大学 2024-03-29 CN disclosed
WO-2023013600-A1 FLUOROPOLYETHER COMPOUND 国立大学法人 東京大学 2023-02-09 WO disclosed