SCHEMBL28017623

SCHEMBL28017623

NCc1ccc(-c2nc(-c3ccc(Cl)cc3)[nH]c2-c2ccc(CN)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 12/20 0.66
MAPK12 P53778 12/20 0.66
MAPK11 Q15759 12/20 0.66
MAPK14 Q16539 12/20 0.66
GCGR P47871 11/20 0.66
ALOX5 P09917 1/20 0.65
BRAF P15056 2/20 0.62
RAF1 P04049 3/20 0.59
CYP19A1 P11511 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9748575 0.87 MAPK13 (0.83) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL25008485 0.86 ALOX5 (0.67) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL3956357 0.82 MAPK13 (0.74) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL2127491 0.81 MAPK13 (0.85) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL16511391 0.80 ALOX5 (0.79) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL7236344 0.80 ALOX5 (0.79) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL29587593 0.80 CYP19A1 (0.72) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL6469052 0.80 MAPK13 (0.73) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL6471005 0.80 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14GCGR
SCHEMBL2649730 0.80 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104246548-B Colored filter color material dispersion liquid, colored filter colored resin composition, colored filter and liquid crystal indicator and organic light-emitting display device 大日本印刷株式会社 2016-08-17 CN disclosed
CN-104641294-A Negative photosensitive resin composition NISSAN CHEMICAL IND LTD 2015-05-20 CN disclosed