SCHEMBL25009028

SCHEMBL25009028

Nc1ccc(-c2cccc3cccc(-c4ccccc4F)c23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
HSD17B10 Q99714 4/20 0.47
TSHR P16473 2/20 0.47
MAPK1 P28482 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ATM Q13315 1/20 0.47
CASP1 P29466 2/20 0.42
CASP7 P55210 2/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
HIF1A Q16665 1/20 0.42
KDR P35968 3/20 0.41
KIT P10721 2/20 0.41
FLT3 P36888 2/20 0.41
PRKCZ Q05513 1/20 0.40
BACE1 P56817 1/20 0.40
CYP3A4 P08684 2/20 0.39
PABPC1 P11940 1/20 0.39
DNMT1 P26358 1/20 0.39
MAPT P10636 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25009769 0.84 KDR (0.50) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL24901133 0.83 HSD17B10 (0.56) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL25009471 0.83 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL24901302 0.82 HSD17B10 (0.60) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL3165600 0.81 ALDH1A1 (0.52) ALDH1A1HSD17B10L3MBTL1TP53PRKCZ
SCHEMBL25009045 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL25008870 0.80 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL25008869 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL29315061 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL29315474 0.78 TAAR1 (0.62) ALDH1A1HSD17B10TSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244961-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-07-18 US disclosed
US-20240244961-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2024-07-18 US disclosed
WO-2023011028-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240244961-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS AOX1, AOC2, OSTC ALDH1A1 643/4885HSD17B10 2130/4885TSHR 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.