SCHEMBL24901133

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24901302	0.98	HSD17B10 (0.60)	HSD17B10CYP3A4TAAR1TDP1ALDH1A1
	SCHEMBL30268605	0.87	ALDH1A1 (0.65)	HSD17B10CYP3A4ALDH1A1TSHRMAPK1
	SCHEMBL10962686	0.87	ALDH1A1 (0.65)	HSD17B10CYP3A4ALDH1A1TSHRMAPK1
	SCHEMBL24067717	0.85	HSD17B10 (0.54)	HSD17B10CYP3A4TAAR1TDP1ALDH1A1
	SCHEMBL24901278	0.84	MAOA (0.57)	HSD17B10CYP3A4ALDH1A1TSHRMAPK1
	SCHEMBL25009769	0.84	KDR (0.50)	HSD17B10CYP3A4TAAR1TDP1ALDH1A1
	SCHEMBL25009028	0.83	ALDH1A1 (0.47)	HSD17B10CYP3A4TAAR1TDP1ALDH1A1
	SCHEMBL16716533	0.83	ALDH1A1 (0.50)	HSD17B10CYP3A4TDP1ALDH1A1TSHR
	SCHEMBL28390018	0.82	PRKCZ (0.50)	HSD17B10CYP3A4TAAR1TDP1ALDH1A1
	SCHEMBL29315474	0.82	TAAR1 (0.62)	HSD17B10TAAR1ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.