Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144390 | 0.90 | CYP2C19 (0.49) | RECQLALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL1144509 | 0.90 | CYP2C19 (0.49) | RECQLALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL14411529 | 0.81 | LMNA (0.41) | RECQLKCNN4CYP2C19HIF1AMAPT | |
| SCHEMBL12666546 | 0.81 | HDAC1 (0.46) | RECQLKCNN4CYP2C19HIF1AMAPT | |
| SCHEMBL9613930 | 0.81 | RECQL (0.44) | RECQLALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL29393902 | 0.79 | NAPRT (0.44) | RECQLALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL28685723 | 0.79 | NAPRT (0.44) | RECQLALDH1A1KCNN4CYP2C19HIF1A | |
| SCHEMBL7868749 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KCNN4CYP2C19HIF1AKMT2A | |
| SCHEMBL5987372 | 0.79 | CA1 (0.38) | RECQLALDH1A1MAPTL3MBTL1HDAC1 | |
| SCHEMBL9829583 | 0.78 | CXCR2 (0.42) | RECQLALDH1A1KCNN4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230044430-A1 | COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES | KRANTZ ALEXANDER (US) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230044430-A1 | COMPOSITION AND METHOD FOR MODIFYING POLYPEPTIDES | PTMS, SRMS, ACP1 | RECQL 3346/4885ALDH1A1 3789/4885KCNN4 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.