Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25010859 | 0.80 | GAA (0.48) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL10916196 | 0.77 | APP (0.44) | GAAALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL9705197 | 0.77 | GAA (0.65) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL25381631 | 0.76 | CFTR (0.47) | GAACFTRHPGDALDH1A1ABCB1 | |
| SCHEMBL653785 | 0.76 | GAA (0.56) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL20298727 | 0.74 | APP (0.48) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL29706660 | 0.74 | GAA (0.50) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL27564755 | 0.72 | GAA (0.48) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL2726928 | 0.72 | GAA (0.54) | GAACFTRHPGDALDH1A1MAPT | |
| SCHEMBL25010664 | 0.71 | KCNH2 (0.47) | GAACFTRMAPTFEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023319-B2 | Carboxylic acid aromatic amides | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-07-02 | — | — | US | disclosed |
| US-11905270-B2 | Carboxylic acid aromatic amides as antagonists of bradykinin B1 receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-02-20 | — | — | US | disclosed |
| US-20230271931-A1 | CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20230271931-A1 | CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20230086179-A1 | CARBOXYLIC ACID AROMATIC AMIDES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-03-23 | — | — | US | disclosed |
| US-20230043209-A1 | CARBOXYLIC ACID AROMATIC AMIDES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11905270-B2 | Carboxylic acid aromatic amides as antagonists of bradykinin B1 receptor | BDKRB1, BDKRB2, HCAR1 | GAA 1630/4885CFTR 1084/4885HPGD 362/4885 |
| US-12023319-B2 | Carboxylic acid aromatic amides | DDC, PAH, NAT1 | GAA 42/4885CFTR 515/4885HPGD 661/4885 |
| US-20230086179-A1 | CARBOXYLIC ACID AROMATIC AMIDES | DDC, PAH, NAT1 | GAA 42/4885CFTR 515/4885HPGD 661/4885 |
| US-20230043209-A1 | CARBOXYLIC ACID AROMATIC AMIDES | DDC, PAH, NAT1 | GAA 42/4885CFTR 515/4885HPGD 661/4885 |
| US-20230271931-A1 | CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR | BDKRB1, BDKRB2, HCAR1 | GAA 1745/4885CFTR 1376/4885HPGD 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.