Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25014625 | 0.86 | ABCB1 (0.38) | MMP1ABCB1ITGA4ITGB7MAOB | |
| SCHEMBL25014618 | 0.71 | MMP1 (0.41) | MMP1ABCB1ITGA4ITGB7MAOB | |
| SCHEMBL25829889 | 0.69 | MEN1 (0.43) | MMP1ABCB1MAOBRAB9AALDH1A1 | |
| SCHEMBL2632623 | 0.68 | EPHX1 (0.53) | MMP1ABCB1MAOBPKMSLC7A5 | |
| SCHEMBL27846893 | 0.68 | EPHX1 (0.53) | MMP1ABCB1MAOBPKMSLC7A5 | |
| SCHEMBL6343323 | 0.68 | EPHX1 (0.53) | MMP1ABCB1MAOBPKMSLC7A5 | |
| SCHEMBL9554305 | 0.67 | ITGA4 (0.51) | ABCB1ITGA4ITGB7RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3707653 | 0.67 | EPHX1 (0.52) | MMP1ABCB1MAOBPKMSLC7A5 | |
| Hydrochloric Acid SCHEMBL6343321 | 0.67 | EPHX1 (0.52) | MMP1ABCB1MAOBPKMSLC7A5 | |
| SCHEMBL10509525 | 0.66 | NPC1 (0.51) | MMP1ABCB1MAOBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024859-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024859-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NLRP1, NLRP3, NOD1 | MMP1 2613/4885ABCB1 250/4885ITGA4 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.