Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822377 | 0.94 | MCL1 (0.34) | MTNR1AMTNR1BPDK2ACHEMCL1 | |
| SCHEMBL31689680 | 0.94 | MCL1 (0.34) | MTNR1AMTNR1BPDK2ACHEMCL1 | |
| SCHEMBL21822553 | 0.84 | NQO2 (0.44) | MTNR1AMTNR1BKMT2AF10F2 | |
| SCHEMBL21822737 | 0.78 | CTSS (0.42) | F10MCL1NQO2 | |
| SCHEMBL31689662 | 0.78 | CTSS (0.42) | F10MCL1NQO2 | |
| SCHEMBL25016833 | 0.76 | KMT2A (0.41) | MTNR1AMTNR1BKMT2AF10F2 | |
| SCHEMBL25017971 | 0.74 | F10 (0.43) | F10F2PRSS1MCL1 | |
| SCHEMBL21822112 | 0.74 | NQO2 (0.37) | F10MCL1NQO2 | |
| SCHEMBL31689687 | 0.74 | NQO2 (0.37) | F10MCL1NQO2 | |
| SCHEMBL30180863 | 0.73 | EPHX1 (0.36) | KMT2AF10MCL1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | MTNR1A 1514/4885MTNR1B 1068/4885KMT2A 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.