SCHEMBL2501968

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2475613	0.94	TSHR (0.51)	TSHRLMNANPC1TP53RAB9A
	SCHEMBL2478980	0.93	USP2 (0.52)	TSHRLMNANPC1TP53RAB9A
	SCHEMBL2475604	0.92	USP2 (0.51)	TSHRLMNATP53ROCK2ALDH1A1
	SCHEMBL2473939	0.90	TSHR (0.60)	TSHRLMNASMN1; SMN2ROCK2CASR
	SCHEMBL2497298	0.90	HDAC1 (0.52)	TSHRLMNATP53SMN1; SMN2ROCK2
	SCHEMBL2475683	0.89	HDAC1 (0.54)	TSHRLMNAALDH1A1HTTMEN1
	SCHEMBL3230310	0.89	TSHR (0.52)	TSHRLMNANPC1TP53RAB9A
	SCHEMBL3829337	0.88	OPRM1 (0.52)	TSHRTP53SMN1; SMN2ROCK2CASR
	SCHEMBL2475705	0.88	KDM1A (0.51)	TSHRLMNANPC1TP53RAB9A
	SCHEMBL2473883	0.88	TSHR (0.57)	TSHRLMNANPC1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.