Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.65 |
| ▸ | PPARA | Q07869 | 13/20 | 0.65 |
| ▸ | SRR | Q9GZT4 | 3/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501988 | 1.00 | PPARG (0.65) | PPARGPPARASRRACEPSAT1 | |
| SCHEMBL1486321 | 0.93 | SRR (0.62) | PPARGPPARASRRACE | |
| SCHEMBL1486323 | 0.93 | SRR (0.62) | PPARGPPARASRRACE | |
| SCHEMBL2626716 | 0.93 | SRR (0.62) | PPARGPPARASRRACE | |
| SCHEMBL5339462 | 0.84 | PPARG (0.71) | PPARGPPARA | |
| SCHEMBL5309440 | 0.84 | PPARG (0.71) | PPARGPPARA | |
| SCHEMBL4144997 | 0.83 | SLC7A5 (0.56) | PPARGPPARASRRACEPSAT1 | |
| SCHEMBL4145000 | 0.83 | SLC7A5 (0.56) | PPARGPPARASRRACEPSAT1 | |
| SCHEMBL2053 | 0.83 | SRR (0.53) | PPARGPPARASRRACE | |
| SCHEMBL5349207 | 0.80 | SRR (0.50) | PPARGPPARASRRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| US-20080318923-A1 | 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318923-A1 | 1,3-Dihydro-2H-Indole-2-One Compound and Pyrrolidine-2-One Compound Fused With Aromatic Heterocycle | AVPR1B, AVPR1A, AVPR2 | PPARG 1291/4885PPARA 1249/4885SRR 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.