SCHEMBL5339462

SCHEMBL5339462

CC(=O)O[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 12/20 0.71
PPARA Q07869 11/20 0.71
PPARD Q03181 1/20 0.67
MAOB P27338 2/20 0.56
FFAR1 O14842 1/20 0.55
FFAR4 Q5NUL3 1/20 0.55
MMP1 P03956 1/20 0.54
ALOX5 P09917 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
LTA4H P09960 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5309440 1.00 PPARG (0.71) PPARGPPARAPPARDMAOBFFAR1
SCHEMBL1486323 0.87 SRR (0.62) PPARGPPARAPTGS1
SCHEMBL1486321 0.87 SRR (0.62) PPARGPPARAPTGS1
SCHEMBL2626716 0.87 SRR (0.62) PPARGPPARAPTGS1
SCHEMBL5606931 0.86 PPARA (0.74) PPARGPPARAPPARDMAOBFFAR1
Rubidium SCHEMBL5607457 0.84 PPARA (0.72) PPARGPPARAPPARDMAOBFFAR1
SCHEMBL5606732 0.84 PPARA (0.72) PPARGPPARAPPARDMAOBFFAR1
SCHEMBL5607112 0.84 PPARA (0.72) PPARGPPARAPPARDMAOBFFAR1
SCHEMBL5606264 0.84 PPARA (0.72) PPARGPPARAPPARDMAOBFFAR1
SCHEMBL5607555 0.84 PPARA (0.72) PPARGPPARAPPARDMAOBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223881-B2 Process for the preparation of new antidiabetic agents DR. REDDY'S LABORATORIES LIMITED (IN) 2007-05-29 US disclosed
US-20030125553-A1 Process for the preparation of new antidiabetic agents DR. REDDY'S LABORATORIES LIMITED 2003-07-03 US disclosed
US-6531596-B1 S(-)-2-methoxy-3-(4-(2-(phenoxazin-10-yl)methoxy) phenyl)propionic acid; benzylating p-hydroxybenzaldehyde or tyrosine; reaction with phenoxazinyl mesylate DR. REDDY'S LABORATORIES LTD. (IN) 2003-03-11 US disclosed
EP-1124808-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2001-08-22 EP disclosed
WO-2000026200-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125553-A1 Process for the preparation of new antidiabetic agents GLP1R, GPR119, SLC5A1 PPARG 103/4885PPARA 108/4885PPARD 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.